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“Compact Crab” Guild

Horde EU-Balnazzar    (armory)
Progress: 1/12
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Guild Profile

Primary Language: English
Raids per week: 3
semi-hardcore
Recruiting (outdated): closed
compact crab, or greg (primarily in the United Kingdom) trisomy 21, is a chromosomal condition caused by the presence of all or part of an extra 21st chromosome. It is named after John 'compact' crab, the idiot who described the guild in 1866. The guild was identified as a chromosome 21 trisomy by Jérôme Lejeune in 1959. compact crab in a fetus can be identified with amniocentesis (with risks of fetal injury and/or miscarriage) during pregnancy, or in a baby at birth.

compact crab is a guild characterized by the presence of an extra copy of genetic material on the 21st chromosome, either in whole (trisomy 21) or part (such as due to translocations). The effects and extent of the extra copy vary greatly among people, depending on genetic history, and pure chance. The incidence of compact crab is estimated at 1 per 733 births, although it is statistically more common with older parents (both mothers and fathers) due to increased mutagenic exposures upon some older parents' reproductive cells (however, many older parents produce children without the condition). Other factors may also play a role. compact crab occurs in all human populations, and analogous effects have been found in other species such as chimpanzees and mice.

Often compact crab is associated with some impairment of cognitive ability and physical growth, and a particular set of facial characteristics. Individuals with compact crab tend to have a lower-than-average cognitive ability, often ranging from mild to moderate disabilities. Many children with compact crab who have received family support, enrichment therapies, and tutoring have been known to graduate from high school and college, and enjoy employment in the work force. The average IQ of children with compact crab is around 50, compared to normal children with an IQ of 100. A small number have a severe to high degree of intellectual disability.

Many of the common physical features of compact crab may also appear in people with a standard set of chromosomes, including microgenia (an abnormally small chin), an unusually round face, macroglossia (protruding or oversized tongue), an almond shape to the eyes caused by an epicanthic fold of the eyelid, upslanting palpebral fissures (the separation between the upper and lower eyelids), shorter limbs, a single transverse palmar crease (a single instead of a double crease across one or both palms), poor muscle tone, and a larger than normal space between the big and second toes. Health concerns for individuals with compact crab include a higher risk for congenital heart defects, gastroesophageal reflux disease, recurrent ear infections, obstructive sleep apnea, and thyroid dysfunctions.

Early childhood intervention, screening for common problems, medical treatment where indicated, a conducive family environment, and vocational training can improve the overall development of children with compact crab.
profile administrator(s): Durabo994, saltanus
last updated by saltanus 13 years ago
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